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Bioanalytical Development Public Health Scientist

Save Lives and Create Futures with our Mass Spectrometry team in the Newborn Screening (NBS) unit. The NBS unit's primary purpose is to provide timely and accurate testing for North Carolinians to identify potentially life-threatening conditions in newborns.
 
This newly created position will work with the Tandem Mass Spectrometry (MS/MS) Laboratory of the Newborn Screening Unit of the State Laboratory of Public Health. The primary purpose of the MS/MS laboratory is to perform biochemical analyses of dried blood spot specimens to detect Fatty Acid Oxidation Disorders, Organic Acid Disorders, Amino Acid Disorders and Lysosomal Storage Disorders in newborns.
 
The Mass Spectrometry and Bioanalytical Development Scientist's primary purpose is to provide professional and technical direction for method development and implementation, quality assurance, staff training, and problem resolution of clinical chemistry testing associated with metabolic disorders detected during newborn screening. This position is responsible for the development and performance of advanced laboratory testing technologies, such as second tier mass spectrometry and HPLC-MS to characterize human biochemical response to metabolic disorders and reduce false positive rates. The incumbent will independently perform highly complex and unusual analytical procedures to separate and purify organic molecules.
 
This position will report to the NBS Unit Manager and is responsible for overseeing method development and technology transfer for the Tandem Mass Spectrometry Laboratory. The clinical chemistry assays utilized are typically laboratory developed tests that require advanced training and experience.
 
Duties include, but are not limited to:
  •  Evaluating available mass spectrometric and High-Performance Liquid Chromatography (HPLC) methods
  • Performing applied research to optimize the detection of a variety of analytes from dried bloodspots (DBS)
  • Publishing scientific data and findings in relevant high impact journals
  • Attending scientific meetings, seminars, and conventions to keep informed about latest developments in technology and the field of newborn screening and clinical chemistry
  • Developing technical training programs to meet laboratory needs, including determining training objectives and identifying resources
  • Assisting with the preparation of specifications for new instrument acquisition
  • Advising and consulting with laboratory management on purchase of analytical instrumentation and implementation of new technology
  • Establishing quality control and assurance measurements and records for clinical chemistry testing procedures and processes
  • Collaborating with universities and other institutions on various data mining and study projects to enhance the testing program

Education Requirements: Doctorate degree in analytical chemistry, molecular biology, medical genetics, microbiology, immunology or a related field.

Job Location: 4312 District Drive, Raleigh NC 27607.